Peter Crack, Associate Professor of The University of Melbourne, Melbourne, Australia. Dr Peter Crack PhD is head of the Neuropharmacology Research Group in the Department of Pharmacology and Therapeutics at the University of Melbourne, Melbourne, Australia. His group’s research interest focuses on the mechanisms of cell death seen in neural injury and the effect of oxidative stress and neuroinflammation in contributing to neural cell death, in both acute and chronic neuropathologies. In investigating these mechanisms there is a focus on traumatic brain injury (TBI) as a representative of acute neuropathology and Alzheimer’s disease (AD) and Parkinson’s disease (PD) as representatives of chronic neuropathologies. The group seeks to find similarities in disease propagation and progression and is interested in the role of the immune system and its components, specifically type-1 IFN signalling, in both the central and peripheral contribution to the outcome in TBI, AD and PD.